48,836
edits
Difference between revisions of "Endometrial hyperplasia"
Jump to navigation
Jump to search
→Endometrial hyperplasia with secretory changes
| Line 214: | Line 214: | ||
*#Cytoplasmic vacuolization. | *#Cytoplasmic vacuolization. | ||
*#Intraluminal secretions. | *#Intraluminal secretions. | ||
* | *Proliferative-type epithelium. † | ||
**Mitoses. | |||
**Nuclear atypia. | |||
**Pseudostratified epithelium. | |||
Notes: | Notes: | ||
*Bell and Ostrezega<ref name=pmid3610133>{{Cite journal | last1 = Bell | first1 = CD. | last2 = Ostrezega | first2 = E. | title = The significance of secretory features and coincident hyperplastic changes in endometrial biopsy specimens. | journal = Hum Pathol | volume = 18 | issue = 8 | pages = 830-8 | month = Aug | year = 1987 | doi = | PMID = 3610133 }}</ref> give a laundry list for differentiating ''benign secretory endometrium'' from ''hyperplasia with secretory changes'': focal architectural abnormalities, metaplastic ciliated & "clear" cells, sharp luminal border, epithelial pseudopalisading, nuclear atypia, vesicular nuclei, mitoses. | * † This is ''not'' precisely defined. I suppose it is some of the things Bell and Ostrezega<ref name=pmid3610133/> mention (mitoses, nuclear atypia, pseudostratified epithelium). | ||
**Bell and Ostrezega<ref name=pmid3610133>{{Cite journal | last1 = Bell | first1 = CD. | last2 = Ostrezega | first2 = E. | title = The significance of secretory features and coincident hyperplastic changes in endometrial biopsy specimens. | journal = Hum Pathol | volume = 18 | issue = 8 | pages = 830-8 | month = Aug | year = 1987 | doi = | PMID = 3610133 }}</ref> give a laundry list for differentiating ''benign secretory endometrium'' from ''hyperplasia with secretory changes'': focal architectural abnormalities, metaplastic ciliated & "clear" cells, sharp luminal border, epithelial pseudopalisading, nuclear atypia, vesicular nuclei, mitoses. | |||
DDx: | DDx: | ||