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Difference between revisions of "Sjögren syndrome"
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→Diagnostic criteria: re-work
(→Diagnostic criteria: re-work -- update guidelines) |
(→Diagnostic criteria: re-work) |
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===Diagnostic criteria=== | ===Diagnostic criteria=== | ||
European criteria of 2002:<ref name=pmid12006334>{{Cite journal | last1 = Vitali | first1 = C. | last2 = Bombardieri | first2 = S. | last3 = Jonsson | first3 = R. | last4 = Moutsopoulos | first4 = HM. | last5 = Alexander | first5 = EL. | last6 = Carsons | first6 = SE. | last7 = Daniels | first7 = TE. | last8 = Fox | first8 = PC. | last9 = Fox | first9 = RI. | title = Classification criteria for Sjögren's syndrome: a revised version of the European criteria proposed by the American-European Consensus Group. | journal = Ann Rheum Dis | volume = 61 | issue = 6 | pages = 554-8 | month = Jun | year = 2002 | doi = | PMID = 12006334 | PMC =1754137 }} | |||
</ref> | </ref> | ||
{| class="wikitable sortable" | {| class="wikitable sortable" | ||
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|- | |- | ||
| Histology | | Histology | ||
| labial minor salivary gland biopsy focus score > 1.0/mm*mm | | labial minor salivary gland biopsy focus score >= 1.0/ 4 mm*mm; definition: multiple lymphocytic foci with >50 lymphocytes adjacent to mucinous acini, evaluated in 4 mm*mm of glandular tissue | ||
| pathology | | pathology | ||
|} | |} | ||
The diagnosis is made if either:<ref name=pmid12006334/> | |||
#Four of six criteria required, must include either autoantibodies or histology. | |||
#Three of the four objective (non-history) criteria are met. | |||
==Microscopic== | ==Microscopic== | ||