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Difference between revisions of "Sjögren syndrome"
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→Diagnostic criteria: re-work -- update guidelines
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===Diagnostic criteria=== | ===Diagnostic criteria=== | ||
Four of six criteria required, must include either autoantibodies or histology:<ref>{{Cite journal | last1 = | Four of six criteria required, must include either autoantibodies or histology:<ref>{{Cite journal | last1 = Vitali | first1 = C. | last2 = Bombardieri | first2 = S. | last3 = Jonsson | first3 = R. | last4 = Moutsopoulos | first4 = HM. | last5 = Alexander | first5 = EL. | last6 = Carsons | first6 = SE. | last7 = Daniels | first7 = TE. | last8 = Fox | first8 = PC. | last9 = Fox | first9 = RI. | title = Classification criteria for Sjögren's syndrome: a revised version of the European criteria proposed by the American-European Consensus Group. | journal = Ann Rheum Dis | volume = 61 | issue = 6 | pages = 554-8 | month = Jun | year = 2002 | doi = | PMID = 12006334 | PMC =1754137 }} | ||
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{| class="wikitable sortable" | {| class="wikitable sortable" | ||
! Criteria | ! Criteria | ||
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|- | |- | ||
| Oral symptoms | | Oral symptoms | ||
| any: (1) dry mouth > 3 months, (2) require fluids for swallowing, (3) swollen salivary glands | | any: (1) dry mouth > 3 months, (2) require fluids for swallowing, (3) swollen salivary glands (adults) | ||
| history | | history | ||
|- | |- | ||
| Oral signs | | Oral signs | ||
| any: (1) low salivary flow, (2) salivary scintigraphy positive (3) sialography positive | | any: (1) low salivary flow test positive, (2) salivary scintigraphy positive (3) (parotid) sialography positive | ||
| clinical test | | clinical test | ||
|- | |- | ||
| Ocular symptoms | | Ocular symptoms | ||
| any: (1) dry eye > 3 months, (2) need artifical tears >3x/day, (3) | | any: (1) dry eye > 3 months, (2) need artifical tears >3x/day, (3) sand or gravel in the eyes sensation | ||
| history | | history | ||
|- | |- | ||
| Ocular signs | | Ocular signs | ||
| any: (1) Schirmer's test positive, (2) | | any: (1) Schirmer's test positive, (2) ocular dye test positive | ||
| clinical test | | clinical test | ||
|- | |- | ||
| Autoantibodies | | Autoantibodies | ||
| | | anti-SSA/Ro and/or anti-SSB/La | ||
| serology | | serology | ||
|- | |- | ||
| Line 45: | Line 46: | ||
| pathology | | pathology | ||
|} | |} | ||
==Microscopic== | ==Microscopic== | ||