Difference between revisions of "Lymph nodes"

Haematopathology and lymphoma is dealt with in the ''[[haematopathology]]'' article.  This article covers the basics of lymph nodes.  Lymph node pathology is dealt with in the ''[[lymph node pathology]]'' article.

Haematopathology and lymphoma is dealt with in the ''[[haematopathology]]'' article.  This article covers the basics of lymph nodes.  Lymph node pathology is dealt with in the ''[[lymph node pathology]]'' article.

===Normal (clinical)===

===Normal (clinical)===

*Round.

*Round.

**What qualifies for "large" depends on the location in the body.

**What qualifies for "large" depends on the location in the body.

Normal:

Normal:

*Firm (relative to adipose tissue).

*Firm (relative to adipose tissue).

**Subtle lobulation (~1 mm) on section suggestive of ''follicular lymphoma''.<ref>DB. 5 August 2010.</ref>

**Subtle lobulation (~1 mm) on section suggestive of ''follicular lymphoma''.<ref>DB. 5 August 2010.</ref>

==LN architecture==

==LN architecture==

Lymph node architecture (superficial to deep):<ref name=Ref_WFH4_206-8>{{Ref WFH4|206-8}}</ref>

Lymph node architecture (superficial to deep):<ref name=Ref_WFH4_206-8>{{Ref WFH4|206-8}}</ref>

{{Main|Lymph node pathology}}

{{Main|Lymph node pathology}}

LNs are very important in [[cancer staging]] and are, in many contexts, sampled routinely.   

LNs are very important in [[cancer staging]] and are, in many contexts, sampled routinely.   

*[[Malignant melanoma#Sentinel lymph node panel|Malignant melanoma]] - first context in which SLN sampling was done.

*[[Malignant melanoma#Sentinel lymph node panel|Malignant melanoma]] - first context in which SLN sampling was done.

*[[Haematopathology]].

*[[Haematopathology]].

*[[Lymph node pathology]].

*[[Lymph node pathology]].