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Difference between revisions of "Common variable immunodeficiency"
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Common variable immunodeficiency (view source)
Revision as of 04:50, 7 March 2013
, 04:50, 7 March 2013→Microscopic: make table
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*[[Graft versus host disease]]. | *[[Graft versus host disease]]. | ||
Features by site in the GI tract:<ref name=pmid18043034>{{Cite journal | last1 = Daniels | first1 = JA. | last2 = Lederman | first2 = HM. | last3 = Maitra | first3 = A. | last4 = Montgomery | first4 = EA. | title = Gastrointestinal tract pathology in patients with common variable immunodeficiency (CVID): a clinicopathologic study and review. | journal = Am J Surg Pathol | volume = 31 | issue = 12 | pages = 1800-12 | month = Dec | year = 2007 | doi = 10.1097/PAS.0b013e3180cab60c | PMID = 18043034 }}</ref> | |||
Features | {| class="wikitable sortable" | ||
!Site | |||
!Features | |||
|- | |||
| Esophagus | |||
| intraepithelial PMNs & candida +/-abundant intraepithelial lymphocytes | |||
|- | |||
| Stomach | |||
| lack of [[plasma cell]]s (~2/3 of individuals), lymphoid aggregates (common), +/-[[lymphocytic gastritis]], +/-intraepithelial neutrophils, +/-infections ([[CMV]], [[H. pylori]], [[cryptosporidium]]) | |||
|- | |||
| Small bowel | |||
| villous blunting (>80% of individuals), decreased plasma cells (~2/3 of individuals), lymphoid aggregates (~1/2 of individuals), +/-neutrophils + infections (CMV, cryptosporidium) | |||
|- | |||
| Large bowel | |||
| decreased plasma cells, lymphoid aggregates, +/-apparent apoptosis | |||
|} | |||
==See also== | ==See also== | ||