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=Introduction= | =Introduction= | ||
*Most cervix cancer is squamous cell carcinoma. | ==Overview== | ||
*Most cervix cancer is [[squamous cell carcinoma of the uterine cervix|squamous cell carcinoma]]. | |||
**An effective screening test to detect this is the ''Pap test'', which is dealt with in the ''[[gynecologic cytopathology]]'' article. | **An effective screening test to detect this is the ''Pap test'', which is dealt with in the ''[[gynecologic cytopathology]]'' article. | ||
*The work-up of an abnormal ''Pap test'' is a ''colposcopic examination'' and biopsies, which are the topic of ''this'' article. | *The work-up of an abnormal ''Pap test'' is a ''colposcopic examination'' and biopsies, which are the topic of ''this'' article. | ||
==Colposcopic examination== | |||
*Performed by gynecologists. | |||
*Exam usually includes the application of acetic acid to help identify lesions for biopsy. | |||
**[[cervical intraepithelial neoplasia|Neoplastic cervical lesions]] are typically white.<ref name=pmid23224202>{{Cite journal | last1 = Zonios | first1 = G. | title = Reflectance model for acetowhite epithelium. | journal = J Biomed Opt | volume = 17 | issue = 8 | pages = 87003-1 | month = Aug | year = 2012 | doi = 10.1117/1.JBO.17.8.087003 | PMID = 23224202 }}</ref> | |||
***[[Squamous metaplasia of the uterine cervix|Squamous metaplasia]] is also white.<ref name=pmid19256708>{{Cite journal | last1 = Li | first1 = W. | last2 = Venkataraman | first2 = S. | last3 = Gustafsson | first3 = U. | last4 = Oyama | first4 = JC. | last5 = Ferris | first5 = DG. | last6 = Lieberman | first6 = RW. | title = Using acetowhite opacity index for detecting cervical intraepithelial neoplasia. | journal = J Biomed Opt | volume = 14 | issue = 1 | pages = 014020 | month = | year = | doi = 10.1117/1.3079810 | PMID = 19256708 }}</ref> | |||
==Cervical specimens== | ==Cervical specimens== |
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