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==Abnormal== | ==Abnormal== | ||
*CD4>CD8 predominance classically seen in: | *CD4>CD8 predominance classically seen in: | ||
**Sarcoidosis. | **[[Sarcoidosis]]. | ||
**Hodgkin's lymphoma. | **[[Hodgkin's lymphoma]]. | ||
*T cell lymphoma - loss of one of the T-cell markers (CD2, CD3, CD5 or CD7). | *T cell lymphoma - loss of one of the T-cell markers (CD2, CD3, CD5 or CD7). | ||
**CD7 is usually the first to be lost. | **CD7 is usually the first to be lost. | ||
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*CD10. | *CD10. | ||
**Germinal centre marker. | **Germinal centre marker. | ||
**+ve in: follicular | **+ve in: [[follicular lymphoma]], [[Burkitt lymphoma]], precursor lymphoblastic leukemia. | ||
*CD19. | *CD19. | ||
**B cell marker. | **B cell marker. | ||
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**Should be ~=CD20. | **Should be ~=CD20. | ||
*CD23. | *CD23. | ||
**+ve in CLL/SLL. | **+ve in [[chronic lymphocytic leukemia|CLL/SLL]]. | ||
*FMC7 | *FMC7 | ||
**B cell marker. | **B cell marker. |
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