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*High-grade anal intraepithelial neoplasia (HGAIN). | *High-grade anal intraepithelial neoplasia (HGAIN). | ||
*Low-grade anal intraepithelial neoplasia (LGAIN). | *Low-grade anal intraepithelial neoplasia (LGAIN). | ||
===Sign out=== | |||
<pre> | |||
SKIN LESION, PERIANAL, BIOPSY: | |||
- ANAL INTRAEPITHELIAL NEOPLASIA 3 (SEVERE DYSPLASIA), WARTY-TYPE. | |||
- MARGIN POSITIVE FOR ANAL INTRAEPITHELIAL NEOPLASIA 3. | |||
</pre> | |||
====Micro==== | |||
There is dysplastic squamous epithelium with coarse chromatin, nuclear hyperchromasia, | |||
nuclear enlargement, irregular nuclear membranes, and an increase nuclear-to-cytoplasmic | |||
ratio. Mitotic activity is abundant. Several atypical mitoses are identified. | |||
The dysplastic squamous epithelium shows minimal maturation toward the surface. | |||
Inflammation at the dermal-epidermal interface is minimal and the dermal-epidermal interface is well-demarcated | |||
=Anal cancer= | =Anal cancer= |
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