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Difference between revisions of "Uterine cervix"
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→Tubal metaplasia of the uterine cervix
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**Peg cells - "tall" and "skinny". | **Peg cells - "tall" and "skinny". | ||
***Columnar/golf tee-like appearance. | ***Columnar/golf tee-like appearance. | ||
** | **Ciliated cells - cilia, pale cytoplasm, round central nucleus. | ||
**Secretory cells - non-ciliated, basophilic cytoplasm, round small basal nuclei. | |||
DDx: | DDx: | ||
*[[Endocervical adenocarcinoma in situ]]. | *[[Endocervical adenocarcinoma in situ]]. | ||
Image: | |||
*[http://www.nature.com/modpathol/journal/v13/n3/fig_tab/3880047f17.html Tubal metaplasia (nature.com)]. | |||
===IHC=== | ===IHC=== | ||
Features:<ref name=pmid8803599>{{Cite journal | last1 = Marques | first1 = T. | last2 = Andrade | first2 = LA. | last3 = Vassallo | first3 = J. | title = Endocervical tubal metaplasia and adenocarcinoma in situ: role of immunohistochemistry for carcinoembryonic antigen and vimentin in differential diagnosis. | journal = Histopathology | volume = 28 | issue = 6 | pages = 549-50 | month = Jun | year = 1996 | doi = | PMID = 8803599 }}</ref> | Features:<ref name=pmid8803599>{{Cite journal | last1 = Marques | first1 = T. | last2 = Andrade | first2 = LA. | last3 = Vassallo | first3 = J. | title = Endocervical tubal metaplasia and adenocarcinoma in situ: role of immunohistochemistry for carcinoembryonic antigen and vimentin in differential diagnosis. | journal = Histopathology | volume = 28 | issue = 6 | pages = 549-50 | month = Jun | year = 1996 | doi = | PMID = 8803599 }}</ref> | ||
*Vimentin +ve. | *Vimentin +ve. | ||
*CEA -ve. | *CEA -ve/+ve. | ||
*p16 -ve.{{fact}} | *p16 -ve.{{fact}} | ||