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(→Papillary urothelial lesions: redo) |
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Urothelial cells in papillae - benign/premalignant/cancerous:<ref>{{Ref GUP|166-175}}</ref><ref name=Ref_WMSP310>{{Ref WMSP|310}}</ref> | Urothelial cells in papillae - benign/premalignant/cancerous:<ref>{{Ref GUP|166-175}}</ref><ref name=Ref_WMSP310>{{Ref WMSP|310}}</ref> | ||
{| class="wikitable" | {| class="wikitable" | ||
! Diagnosis | |||
! Papillae features | |||
! Papillae branching | |||
! Papillae fusion | |||
! Puclear size | |||
! Mitoses | |||
! DDx | |||
! IHC | |||
! Other | |||
! Key feature | |||
|- | |- | ||
| | | [[Urothelial papilloma|Papilloma]] | ||
| '''fat papillae''', <br>'''thick FV core''' | | '''fat papillae''', <br>'''thick FV core''' | ||
| rare | | rare | ||
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| normal (2x lymphocyte) | | normal (2x lymphocyte) | ||
| very rare basal | | very rare basal | ||
| PUNLMP, low gr. PUCC | | [[PUNLMP]], low gr. PUCC | ||
| p53-, CK20+ umbrella cells | | p53-, CK20+ umbrella cells | ||
| cytologically normal | | cytologically normal | ||
| normal cells,<br>fat papillae | | normal cells,<br>fat papillae | ||
|- | |- | ||
| | | [[PUNLMP]] | ||
| '''slender FV core''' | | '''slender FV core''' | ||
| uncommon | | uncommon | ||
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| uniformly enlarged cell pop., <br>slender papillae | | uniformly enlarged cell pop., <br>slender papillae | ||
|- | |- | ||
| | | [[Low grade papillary urothelial carcinoma|Low grade PUCC]] | ||
| slender FV core, <br>'''thick epithelium''' | | slender FV core, <br>'''thick epithelium''' | ||
| frequent | | frequent | ||
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| nuc. pleomorphism, <br> thick epithelium | | nuc. pleomorphism, <br> thick epithelium | ||
|- | |- | ||
| | | [[High grade papillary urothelial carcinoma|High grade PUCC]] | ||
| mixed population | | mixed population | ||
| common | | common |
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