Difference between revisions of "Urothelium"

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100 bytes added ,  01:30, 28 November 2012
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Urothelial cells in papillae - benign/premalignant/cancerous:<ref>{{Ref GUP|166-175}}</ref><ref name=Ref_WMSP310>{{Ref WMSP|310}}</ref>
Urothelial cells in papillae - benign/premalignant/cancerous:<ref>{{Ref GUP|166-175}}</ref><ref name=Ref_WMSP310>{{Ref WMSP|310}}</ref>
{| class="wikitable"
{| class="wikitable"
| Diagnosis
! Diagnosis
| papillae features
! Papillae features
| papillae branching
! Papillae branching
| papillae fusion
! Papillae fusion
| nuclear size
! Puclear size
| mitoses
! Mitoses
| DDx
! DDx
| IHC
! IHC
| Other
! Other
| Key feature
! Key feature
|-
|-
| '''Papilloma'''
| [[Urothelial papilloma|Papilloma]]
| '''fat papillae''', <br>'''thick FV core'''
| '''fat papillae''', <br>'''thick FV core'''
| rare
| rare
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| normal (2x lymphocyte)
| normal (2x lymphocyte)
| very rare basal
| very rare basal
| PUNLMP, low gr. PUCC
| [[PUNLMP]], low gr. PUCC
| p53-, CK20+ umbrella cells
| p53-, CK20+ umbrella cells
| cytologically normal
| cytologically normal
| normal cells,<br>fat papillae
| normal cells,<br>fat papillae
|-
|-
| '''PUNLMP'''
| [[PUNLMP]]
| '''slender FV core'''
| '''slender FV core'''
| uncommon
| uncommon
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| uniformly enlarged cell pop., <br>slender papillae
| uniformly enlarged cell pop., <br>slender papillae
|-
|-
| '''low grade PUCC'''
| [[Low grade papillary urothelial carcinoma|Low grade PUCC]]
| slender FV core, <br>'''thick epithelium'''  
| slender FV core, <br>'''thick epithelium'''  
| frequent
| frequent
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| nuc. pleomorphism, <br> thick epithelium
| nuc. pleomorphism, <br> thick epithelium
|-
|-
| '''high grade PUCC'''
| [[High grade papillary urothelial carcinoma|High grade PUCC]]
| mixed population
| mixed population
| common
| common
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