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Difference between revisions of "Uterine cervix"
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m
→CIN I
(→Cervical intraepithelial neoplasia: re-work) |
m (→CIN I) |
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====CIN I==== | ====CIN I==== | ||
Features - CIN I:<ref name=Ref_PBoD1075-6>{{Ref PBoD|1075-6}}</ref> | Features - CIN I:<ref name=Ref_PBoD1075-6>{{Ref PBoD|1075-6}}</ref> | ||
*Cytoplasmic halos | *"Koilocytic atypia":<ref name=Ref_GP146>{{Ref GP|146}}</ref> | ||
*Nuclear enlargement | **Cytoplasmic halos. | ||
*Binucleation may be seen (cytopathic effect of [[HPV]]).<ref name=pmid11491378>{{cite journal |author=Roteli-Martins CM, Derchain SF, Martinez EZ, Siqueira SA, Alves VA, Syrjänen KJ |title=Morphological diagnosis of HPV lesions and cervical intraepithelial neoplasia (CIN) is highly reproducible |journal=Clin Exp Obstet Gynecol |volume=28 |issue=2 |pages=78–80 |year=2001 |pmid=11491378 |doi= |url=}}</ref> | **Nuclear enlargement >=3:1 enlarged nucleus:normal nucleus. | ||
**Nuclear membrane irregularities. | |||
**Nuclear hyperchromasia. | |||
**Coarse chromatin. | |||
**Binucleation may be seen (cytopathic effect of [[HPV]]).<ref name=pmid11491378>{{cite journal |author=Roteli-Martins CM, Derchain SF, Martinez EZ, Siqueira SA, Alves VA, Syrjänen KJ |title=Morphological diagnosis of HPV lesions and cervical intraepithelial neoplasia (CIN) is highly reproducible |journal=Clin Exp Obstet Gynecol |volume=28 |issue=2 |pages=78–80 |year=2001 |pmid=11491378 |doi= |url=}}</ref> | |||
Note: | |||
*Atypical cells usually close to basement membrane. | *Atypical cells usually close to basement membrane. | ||
**May be seen, focally, in the upper layers.<ref name=Ref_GP146>{{Ref GP|146}}</ref> | **May be seen, focally, in the upper layers.<ref name=Ref_GP146>{{Ref GP|146}}</ref> | ||