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Difference between revisions of "Fibroblastic/myofibroblastic tumours"
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Fibroblastic/myofibroblastic tumours (view source)
Revision as of 20:03, 10 September 2012
, 20:03, 10 September 2012→Calcifying fibrous tumour: +myofibroma
(re-arr) |
(→Calcifying fibrous tumour: +myofibroma) |
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| Line 276: | Line 276: | ||
*Psammomatous calcifications. | *Psammomatous calcifications. | ||
*Focal plasma cells at the periphery. | *Focal plasma cells at the periphery. | ||
==Myofibroma== | |||
===General=== | |||
*Benign. | |||
*Often < 2 years old; however, may be seen in adults. | |||
*Not common.<ref name=pmid20038894>{{Cite journal | last1 = Brasileiro | first1 = BF. | last2 = Martins-Filho | first2 = PR. | last3 = Piva | first3 = MR. | last4 = da Silva | first4 = LC. | last5 = Nonaka | first5 = CF. | last6 = Miguel | first6 = MC. | title = Myofibroma of the oral cavity. A rare spindle cell neoplasm. | journal = Med Oral Patol Oral Cir Bucal | volume = 15 | issue = 4 | pages = e596-600 | month = Jul | year = 2010 | doi = | PMID = 20038894 | url= http://www.medicinaoral.com/pubmed/medoralv15_i4_p596.pdf }}</ref> | |||
===Gross=== | |||
*Classically (oral) locations: tongue, buccal mucosa, lip.<ref name=pmid20038894/> | |||
===Microscopic=== | |||
Features:<ref name=pmid20038894/> | |||
*Spindle cells with tapering nuclei. | |||
Note: | |||
*Features overlap with [[myopericytoma]].<ref name=pmid16394283>{{cite journal |author=Dray MS, McCarthy SW, Palmer AA, ''et al.'' |title=Myopericytoma: a unifying term for a spectrum of tumours that show overlapping features with myofibroma. A review of 14 cases |journal=J. Clin. Pathol. |volume=59 |issue=1 |pages=67–73 |year=2006 |month=January |pmid=16394283 |pmc=1860256 |doi=10.1136/jcp.2005.028704 |url= }}</ref> | |||
DDx: | |||
*[[Neurofibroma]]. | |||
*[[Leiomyoma]]. | |||
===IHC=== | |||
Features:<ref name=pmid20038894/> | |||
*Vimentin +ve. | |||
*SMA +ve. | |||
*S-100 -ve, | |||
=Occasionally metastasizing= | =Occasionally metastasizing= | ||