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Difference between revisions of "Malignant melanoma"
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→Skin: tweak
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#Architecture: | #Architecture: | ||
#*Sheeting - '''diagnostic'''. | #*Sheeting - '''diagnostic'''. | ||
#*Asymmetry | #*Asymmetry of architecture - as judged from low power magnification. | ||
#Lack of maturation - see below. | #Lack of maturation - see below. | ||
#+/-[[Nuclear atypia]] - esp. nucleoli. | #+/-[[Nuclear atypia]] - esp. nucleoli. | ||
| Line 82: | Line 80: | ||
#**Histologic evidence of trauma. | #**Histologic evidence of trauma. | ||
#***Thick dense ''stratum corneum''. | #***Thick dense ''stratum corneum''. | ||
#+/-Asymmetry of pigmentation. | |||
Maturation - with depth: | Maturation - with depth: | ||
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*Cells get smaller. | *Cells get smaller. | ||
*Mitoses decrease. | *Mitoses decrease. | ||
*Pigmentation | *Pigmentation decreases. | ||
DDx: | DDx: | ||