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Difference between revisions of "Surgical margins"
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→Adequate margins by tumour
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| [[Ductal carcinoma in situ]] | | [[Ductal carcinoma in situ]] | ||
| > 2mm<ref>{{Cite journal | last1 = Dunne | first1 = C. | last2 = Burke | first2 = JP. | last3 = Morrow | first3 = M. | last4 = Kell | first4 = MR. | title = Effect of margin status on local recurrence after breast conservation and radiation therapy for ductal carcinoma in situ. | journal = J Clin Oncol | volume = 27 | issue = 10 | pages = 1615-20 | month = Apr | year = 2009 | doi = 10.1200/JCO.2008.17.5182 | PMID = 19255332 }}</ref>; if < 1 mm patient benefits from radiation<ref name=pmid10320383>{{Cite journal | last1 = Silverstein | first1 = MJ. | last2 = Lagios | first2 = MD. | last3 = Groshen | first3 = S. | last4 = Waisman | first4 = JR. | last5 = Lewinsky | first5 = BS. | last6 = Martino | first6 = S. | last7 = Gamagami | first7 = P. | last8 = Colburn | first8 = WJ. | title = The influence of margin width on local control of ductal carcinoma in situ of the breast. | journal = N Engl J Med | volume = 340 | issue = 19 | pages = 1455-61 | month = May | year = 1999 | doi = 10.1056/NEJM199905133401902 | PMID = 10320383 }}</ref> | |||
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| [[Breast pathology]] | | [[Breast pathology]] | ||
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| cannot be at margin - no consensus beyond that;<ref name=pmid12433599>{{Cite journal | last1 = Singletary | first1 = SE. | title = Surgical margins in patients with early-stage breast cancer treated with breast conservation therapy. | journal = Am J Surg | volume = 184 | issue = 5 | pages = 383-93 | month = Nov | year = 2002 | doi = | PMID = 12433599 }}</ref> no statistical difference between 1 and 2 mm margins for Stage I & II tumours<ref name=pmid18767118>{{Cite journal | last1 = Hardy | first1 = K. | last2 = Fradette | first2 = K. | last3 = Gheorghe | first3 = R. | last4 = Lucman | first4 = L. | last5 = Latosinsky | first5 = S. | title = The impact of margin status on local recurrence following breast conserving therapy for invasive carcinoma in Manitoba. | journal = J Surg Oncol | volume = 98 | issue = 6 | pages = 399-402 | month = Nov | year = 2008 | doi = 10.1002/jso.21126 | PMID = 18767118 }}</ref> | | cannot be at margin - no consensus beyond that;<ref name=pmid12433599>{{Cite journal | last1 = Singletary | first1 = SE. | title = Surgical margins in patients with early-stage breast cancer treated with breast conservation therapy. | journal = Am J Surg | volume = 184 | issue = 5 | pages = 383-93 | month = Nov | year = 2002 | doi = | PMID = 12433599 }}</ref> no statistical difference between 1 and 2 mm margins for Stage I & II tumours<ref name=pmid18767118>{{Cite journal | last1 = Hardy | first1 = K. | last2 = Fradette | first2 = K. | last3 = Gheorghe | first3 = R. | last4 = Lucman | first4 = L. | last5 = Latosinsky | first5 = S. | title = The impact of margin status on local recurrence following breast conserving therapy for invasive carcinoma in Manitoba. | journal = J Surg Oncol | volume = 98 | issue = 6 | pages = 399-402 | month = Nov | year = 2008 | doi = 10.1002/jso.21126 | PMID = 18767118 }}</ref> | ||
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| [[Breast pathology]] | |||
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| [[Sarcoma]] | | [[Sarcoma]] | ||