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Difference between revisions of "Uterine cervix"
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→Uncommon types of cervical cancer: +mesonephric adenocarcinoma
(expand, subdivide) |
(→Uncommon types of cervical cancer: +mesonephric adenocarcinoma) |
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| Line 442: | Line 442: | ||
Like the salivary gland tumour: | Like the salivary gland tumour: | ||
*t(11;19) CRTC1/MAML2.<ref name=pmid19092631/> | *t(11;19) CRTC1/MAML2.<ref name=pmid19092631/> | ||
==Mesonephric adenocarcinoma== | |||
===General=== | |||
*Arises from the [[mesonephric duct remnants]]. | |||
===Microscopic=== | |||
Features:<ref name=Ref_WMSP442>{{Ref WMSP|442}}</ref> | |||
*Nuclear atypia - '''key feature'''. | |||
**Nuclear crowding. | |||
*Variable architecture: | |||
**Tubular, papillary, solid, retiform (net-like<ref>URL: [http://www.thefreedictionary.com/retiform http://www.thefreedictionary.com/retiform]. Accessed on: 25 August 2012.</ref>. | |||
DDx: | |||
*[[Mesonephric duct remnants]]. | |||
*[[Cervical adenocarcinoma]]. | |||
*[[Colorectal adenocarcinoma]]. | |||
*Endometrioid adenocarcinoma. | |||
===IHC=== | |||
Features:<ref name=Ref_WMSP442>{{Ref WMSP|442}}</ref> | |||
*CK7 +ve. | |||
*CD10 +ve. | |||
Others:<ref name=Ref_WMSP442>{{Ref WMSP|442}}</ref> | |||
*CK20 -ve. | |||
*ER -ve. | |||
*PR -ve. | |||
*CEA -ve. | |||
=See also= | =See also= | ||