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Difference between revisions of "Soft tissue lesions"
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→Pleomorphic undifferentiated sarcoma: +IHC
(→Clear cell sarcoma: rm obsolete link, add more image links, rework micro) |
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| Line 249: | Line 249: | ||
DDx: | DDx: | ||
*[[Atypical fibroxanthoma]] (AFX). | *[[Atypical fibroxanthoma]] (AFX) - superficial skin. | ||
*[[Dedifferentiated liposarcoma]]. | *[[Dedifferentiated liposarcoma]]. | ||
*[[Leiomyosarcoma]]. | *[[Leiomyosarcoma]]. | ||
| Line 267: | Line 267: | ||
*PS with inflammation. | *PS with inflammation. | ||
*PUS (not otherwise specified) - wastebasket diagnosis; if neither of the above two apply. | *PUS (not otherwise specified) - wastebasket diagnosis; if neither of the above two apply. | ||
===IHC=== | |||
Exclusionary stains - should be negative: | |||
*AE1/AE3. | |||
*p63. | |||
*Myogenin. | |||
*S-100. | |||
*HMB-45. | |||
Usually negative, may be positive:<ref name=Ref_WMSP613>{{Ref WMSP|613}}</ref> | |||
*Desmin. | |||
*SMA. | |||
Commonly positive: | |||
*CD68.<ref name=Ref_WMSP613>{{Ref WMSP|613}}</ref> | |||
*Vimentin. | |||
=Fibroblastic/myofibroblastic tumours= | =Fibroblastic/myofibroblastic tumours= | ||