48,453
edits
Difference between revisions of "Soft tissue lesions"
Jump to navigation
Jump to search
→Clear cell sarcoma: rm obsolete link, add more image links, rework micro
(→Microscopic: more) |
(→Clear cell sarcoma: rm obsolete link, add more image links, rework micro) |
||
| Line 574: | Line 574: | ||
====Clinical==== | ====Clinical==== | ||
*Usually - deep soft tissue ''or'' extremities. | *Usually - deep soft tissue ''or'' extremities. | ||
**Classically associated with tendons and aponeuroses.<ref>{{Cite journal | last1 = Dim | first1 = DC. | last2 = Cooley | first2 = LD. | last3 = Miranda | first3 = RN. | title = Clear cell sarcoma of tendons and aponeuroses: a review. | journal = Arch Pathol Lab Med | volume = 131 | issue = 1 | pages = 152-6 | month = Jan | year = 2007 | doi = 10.1043/1543-2165(2007)131[152:CCSOTA]2.0.CO;2 | PMID = 17227118 }}</ref> | **Classically associated with tendons and aponeuroses.<ref name=pmid17227118>{{Cite journal | last1 = Dim | first1 = DC. | last2 = Cooley | first2 = LD. | last3 = Miranda | first3 = RN. | title = Clear cell sarcoma of tendons and aponeuroses: a review. | journal = Arch Pathol Lab Med | volume = 131 | issue = 1 | pages = 152-6 | month = Jan | year = 2007 | doi = 10.1043/1543-2165(2007)131[152:CCSOTA]2.0.CO;2 | PMID = 17227118 }}</ref> | ||
*Guarded prognosis. | *Guarded prognosis. | ||
*First described in 1965.<ref>URL: [http://www.informaworld.com/smpp/723576818-750600/ftinterface~db=all~content=a789166263~fulltext=713240928 http://www.informaworld.com/smpp/723576818-750600/ftinterface~db=all~content=a789166263~fulltext=713240928]. Accessed on: 5 May 2010.</ref> | *First described in 1965.<ref>URL: [http://www.informaworld.com/smpp/723576818-750600/ftinterface~db=all~content=a789166263~fulltext=713240928 http://www.informaworld.com/smpp/723576818-750600/ftinterface~db=all~content=a789166263~fulltext=713240928]. Accessed on: 5 May 2010.</ref> | ||
| Line 580: | Line 580: | ||
===Microscopic=== | ===Microscopic=== | ||
Features:<ref name=pmid18300804/> | Features:<ref name=pmid18300804/> | ||
*Architecture: | *Architecture: sheeting ''or'' fascicular (bundles) arrangement. | ||
* | **Fibrous septae - between tumour cells. | ||
*Prominent nucleoli - basophilic - '''key feature'''. | *Tumour cells uniform (low pleomorphism) - spindle-shaped ''or'' epithelioid: | ||
* | **Classically have clear cytoplasm. | ||
**Prominent nucleoli - basophilic - '''key feature'''. | |||
*+/-Binucleation. | **+/-Binucleation. | ||
DDx: | DDx: | ||
| Line 592: | Line 592: | ||
*Carcinoma. | *Carcinoma. | ||
Images: | |||
*[http://commons.wikimedia.org/wiki/File: | *[http://commons.wikimedia.org/wiki/File:Clear_cell_sarcoma_-_intermed_mag.jpg Clear cell sarcoma - intermed. mag. (WC)]. | ||
*[http:// | *[http://commons.wikimedia.org/wiki/File:Clear_cell_sarcoma_-_very_high_mag.jpg Clear cell sarcoma - very high mag. (WC)]. | ||
*[http://commons.wikimedia.org/wiki/File:Clear_cell_sarcoma.Image12.jpg Clear cell sarcoma (WC/Gardner)]. | |||
===IHC=== | ===IHC=== | ||