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Line 84: |
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| |
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| ===Stomach=== | | ===Stomach=== |
| Divided into four types:<ref>URL: [http://www.cap.org/apps/docs/committees/cancer/cancer_protocols/2011/StomachNET_11protocol.pdf http://www.cap.org/apps/docs/committees/cancer/cancer_protocols/2011/StomachNET_11protocol.pdf]. Accessed on: 29 March 2012.</ref>
| | {{Main|Gastric neuroendocrine tumour}} |
| {| class="wikitable sortable" | |
| !Tumour type
| |
| !Relative prevalence
| |
| !Multifocality
| |
| !Tumour size
| |
| !Typical location
| |
| !Clinical
| |
| !Other
| |
| !Histology
| |
| |-
| |
| |Type 1
| |
| | ~75%
| |
| | yes
| |
| | small (5-10 mm)
| |
| | body
| |
| | benign typically, female:male ~ 4:1, 50-60 years
| |
| | chronic atrophic gastritis - usu. autoimmune
| |
| | WDNET, WDNEC
| |
| |-
| |
| |Type 2
| |
| | rare
| |
| | yes
| |
| | small ~15 mm
| |
| | body
| |
| | aggressive, ~50 years old
| |
| | assoc. [[MEN I]], hyperchlorhydia
| |
| | WDNEC, WDNET
| |
| |-
| |
| |Type 3
| |
| | 10-15%
| |
| | no
| |
| | small and large
| |
| | variable location
| |
| | aggressive if >2.0 cm, males > females
| |
| | normal gastrin levels
| |
| | WDNET
| |
| |-
| |
| |Type 4
| |
| | extremely rare
| |
| | no
| |
| | large
| |
| | variable location
| |
| | aggressive (mets usu. at time of Dx), males > females
| |
| | elevated gastrin d/t parietal cell dysfunction
| |
| | PDNEC
| |
| |-
| |
| |}
| |
| Notes:
| |
| *WDNET = well-differentiated neuroendocrine tumour.
| |
| *WDNEC = well-differentiated neuroendocrine carcinoma.
| |
| *PDNEC = poorly-differentiated neuroendocrine carinoma.
| |
|
| |
|
| ===Duodenum=== | | ===Duodenum=== |