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Difference between revisions of "Peripheral nerve sheath tumours"
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Peripheral nerve sheath tumours (view source)
Revision as of 20:12, 12 June 2012
, 20:12, 12 June 2012→Schwannoma: subsections -- for subtypes
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====Schwannoma subtypes==== | ====Schwannoma subtypes==== | ||
There are four:<ref name=pmid12792904>{{cite journal |author=Kurtkaya-Yapicier O, Scheithauer B, Woodruff JM |title=The pathobiologic spectrum of Schwannomas |journal=Histol. Histopathol. |volume=18 |issue=3 |pages=925–34 |year=2003 |month=July |pmid=12792904 |doi= |url=}}</ref> | There are four:<ref name=pmid12792904>{{cite journal |author=Kurtkaya-Yapicier O, Scheithauer B, Woodruff JM |title=The pathobiologic spectrum of Schwannomas |journal=Histol. Histopathol. |volume=18 |issue=3 |pages=925–34 |year=2003 |month=July |pmid=12792904 |doi= |url=}}</ref> | ||
#Conventional schwannoma. | #Conventional schwannoma. | ||
# | #Cellular schwannoma. | ||
#Plexiform schwannoma. | |||
#Plexiform schwannoma | |||
#Melanotic schwannoma. | #Melanotic schwannoma. | ||
=====Conventional schwannoma===== | |||
*Most common. | |||
=====Cellular schwannoma===== | |||
*May mimic [[MPNST]]. | |||
Images: | |||
*[http://path.upmc.edu/cases/case518.html Cellular schwannoma (upmc.edu)]. | |||
=====Plexiform schwannoma===== | |||
*May mimic [[MPNST]] if cellular - esp. in childhood. | |||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:Plexiform_Schwannoma_2.jpg Plexiform schwannoma - low mag. (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:Plexiform_Schwannoma_1.jpg Plexiform schwannoma - high mag. (WC)]. | |||
=====Melanotic schwannoma===== | |||
*May be confused with [[melanoma]]. | |||
*Psammomatous form (''psammomatous melanotic schwannoma'') associated with a heritable disorder ([[Carney complex]]). | |||
Note: | |||
*[[Carney complex]]:<ref name=pmid12792904/> | *[[Carney complex]]:<ref name=pmid12792904/> | ||
**Cutaneous lentigines. | **Cutaneous lentigines. | ||
**Myxomas (skin (subcutaneous), subcutanous, [[Atrial myxoma|heart]]). | **Myxomas (skin (subcutaneous), subcutanous, [[Atrial myxoma|heart]]). | ||
**Endocrine neoplasms. | **Endocrine neoplasms. | ||
Images: | |||
*[http://path.upmc.edu/cases/case387.html Psammomatous melanotic schwannoma - several images (upmc.edu)]. | |||
===IHC=== | ===IHC=== | ||