48,830
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(→Endocervical adenocarcinoma: +DDx) |
(→Endocervical adenocarcinoma in situ: tweak micro - add ref.) |
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===Microscopic=== | ===Microscopic=== | ||
Features: | Features:<ref name=pmid10757337>{{Cite journal | last1 = Zaino | first1 = RJ. | title = Glandular lesions of the uterine cervix. | journal = Mod Pathol | volume = 13 | issue = 3 | pages = 261-74 | month = Mar | year = 2000 | doi = 10.1038/modpathol.3880047 | PMID = 10757337 | url = http://www.nature.com/modpathol/journal/v13/n3/full/3880047a.html }}</ref> | ||
#Nuclear changes - '''key feature''': | |||
**Nuclear crowding. | #*Variable nuclear stratification. | ||
#**Nuclear crowding/pseudostratification. | |||
** | #*Nuclear enlargement. | ||
*+/-Mitoses. | #**Often cigar-shaped nuclei. | ||
* | #*Coarse chromatin. | ||
#*Small nucleolus or nucleoli. | |||
#+/-Mitoses. | |||
#+/-Reduced cytoplasmic mucin. | |||
#Preservation of glandular architecture. | |||
#*Normal gland spacing - lack of complexity. | |||
#*Normal gland depth (subjective). | |||
DDx: | DDx: |
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