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Difference between revisions of "Bone"
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→Others: +osteopetrosis, osteoporosis
(→Paget disease of the bone: fix sp., +assoc. with GCT of bone) |
(→Others: +osteopetrosis, osteoporosis) |
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Recurrent [[chromosomal translocation]]:<ref name=pmid22285042/> | Recurrent [[chromosomal translocation]]:<ref name=pmid22285042/> | ||
*t(16;17)(q22;p13). | *t(16;17)(q22;p13). | ||
==Osteopetrosis== | |||
*[[AKA]] ''marble bone disease''.<ref name=pmid19232111>{{Cite journal | last1 = Stark | first1 = Z. | last2 = Savarirayan | first2 = R. | title = Osteopetrosis. | journal = Orphanet J Rare Dis | volume = 4 | issue = | pages = 5 | month = | year = 2009 | doi = 10.1186/1750-1172-4-5 | PMID = 19232111 | PMC = 2654865 }}</ref> | |||
===General=== | |||
*Rare. | |||
*Genetic - may be autosomal dominant, autosomal recessive or X-linked.<ref name=pmid19232111/> | |||
===Gross=== | |||
*Marbled appearance. | |||
Image: | |||
*[http://www.uaz.edu.mx/histo/pathology/ed/ch_26/c26_s25.htm Osteopetrosis (uaz.edu.mx)]. | |||
===Microscopic=== | |||
Features: | |||
Image: | |||
*[http://bloodjournal.hematologylibrary.org/content/97/7/1947/F2.expansion.html Osteopetrosis (bloodjournal.hematologylibrary.org)].<ref name=pmid11264157>{{Cite journal | last1 = McMahon | first1 = C. | last2 = Will | first2 = A. | last3 = Hu | first3 = P. | last4 = Shah | first4 = GN. | last5 = Sly | first5 = WS. | last6 = Smith | first6 = OP. | title = Bone marrow transplantation corrects osteopetrosis in the carbonic anhydrase II deficiency syndrome. | journal = Blood | volume = 97 | issue = 7 | pages = 1947-50 | month = Apr | year = 2001 | doi = | PMID = 11264157 |URL = http://bloodjournal.hematologylibrary.org/content/97/7/1947.full }}</ref> | |||
==Osteoporosis== | |||
===General=== | |||
*Very common. | |||
===Microscopic=== | |||
Features: | |||
=See also= | =See also= | ||