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Difference between revisions of "Spindle cell lesions"
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→Malignant fibrous histiocytoma
(→Malignant fibrous histiocytoma: bcl-2) |
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*S100 - neural marker, sensitive for malignant melanoma. | *S100 - neural marker, sensitive for malignant melanoma. | ||
*Desmin - smooth muscle. | *Desmin - smooth muscle. | ||
* | *MIB1 - proliferation. | ||
*CD99 - small round cell tumours, considered "slutty", i.e. non-specific, by Dr. Fletcher; useful if membranous stain pattern = Ewing sarcoma/PNET. | *CD99 - small round cell tumours, considered "slutty", i.e. non-specific, by Dr. Fletcher; useful if membranous stain pattern = Ewing sarcoma/PNET. | ||
* | *BCL2 - synovial sarcoma, [[small cell lymphomas]], spindle cell lipoma.<ref name=Ref_DCHH107>{{Ref DCHH|107}}</ref><ref>URL: [http://ajp.amjpathol.org/cgi/content/full/160/3/759 http://ajp.amjpathol.org/cgi/content/full/160/3/759]. Accessed on: 3 August 2010.</ref> | ||
*PGP 9.5. | *PGP 9.5. | ||
*SMMS - smooth muscle. | *SMMS - smooth muscle. | ||
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*Beta-catenin - a small subset of soft tissue lesions: | *Beta-catenin - a small subset of soft tissue lesions: | ||
**Desmoidtype fibromatosis (~70%), solitary fibrous tumour & endometrial stromal sarcoma (~40%), synovial sarcoma (~30%).<ref name=pmid15375433>{{cite journal |author=Ng TL, Gown AM, Barry TS, ''et al.'' |title=Nuclear beta-catenin in mesenchymal tumors |journal=Mod. Pathol. |volume=18 |issue=1 |pages=68–74 |year=2005 |month=January |pmid=15375433 |doi=10.1038/modpathol.3800272 |url=}}</ref> | **Desmoidtype fibromatosis (~70%), solitary fibrous tumour & endometrial stromal sarcoma (~40%), synovial sarcoma (~30%).<ref name=pmid15375433>{{cite journal |author=Ng TL, Gown AM, Barry TS, ''et al.'' |title=Nuclear beta-catenin in mesenchymal tumors |journal=Mod. Pathol. |volume=18 |issue=1 |pages=68–74 |year=2005 |month=January |pmid=15375433 |doi=10.1038/modpathol.3800272 |url=}}</ref> | ||
==See also== | ==See also== | ||