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(→Microscopic: tweak) |
(→Fibroadenoma: more) |
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Management: | Management: | ||
*Local excision | *Local excision -- without a large margin. | ||
===Microscopic=== | ===Microscopic=== | ||
Features | Features:<ref name=Ref_BP110>{{Ref BP|110}}</ref> | ||
*Abundant (intralobular) stroma - most ''' | *Abundant (intralobular) stroma - most '''key feature'''. | ||
**Stroma is usually | **Stroma is usually: | ||
***May be hyalinized (dark pink) if infarcted. | ***White/pale, i.e. [[myxoid stroma|myxoid]], on H&E (normal stroma is pink). | ||
*Compression of glandular elements | ****May be hyalinized (dark pink) if infarcted. | ||
***Paucicellular - typical. | |||
*Compression of glandular elements - very commonly seen. | |||
**Glandular elements have at least two cell layers - epithelial and myoepithelial. | |||
DDx: | DDx: | ||
*[[Phyllodes tumour]] | *[[Phyllodes tumour]] - long slit-like spaces (seen grossly), stroma is more cellular. | ||
**+/-Mitoses, | |||
** | **+/-"Stromal overgrowth" = large area where there is a 'loss of glands'. | ||
**"Stromal overgrowth" large area where there is a 'loss of glands' | |||
*Sarcoma. | *Sarcoma. | ||
*[[PASH]]. | *[[PASH]]. | ||
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Image: | Image: | ||
*[http://radiographics.rsna.org/content/27/suppl_1/S101/F40.expansion.html Infarcted fibroadenoma (rsna.org)].<ref name=pmid18180221>{{Cite journal | last1 = Sabate | first1 = JM. | last2 = Clotet | first2 = M. | last3 = Torrubia | first3 = S. | last4 = Gomez | first4 = A. | last5 = Guerrero | first5 = R. | last6 = de las Heras | first6 = P. | last7 = Lerma | first7 = E. | title = Radiologic evaluation of breast disorders related to pregnancy and lactation. | journal = Radiographics | volume = 27 Suppl 1 | issue = | pages = S101-24 | month = Oct | year = 2007 | doi = 10.1148/rg.27si075505 | PMID = 18180221 }}</ref> | *[http://radiographics.rsna.org/content/27/suppl_1/S101/F40.expansion.html Infarcted fibroadenoma (rsna.org)].<ref name=pmid18180221>{{Cite journal | last1 = Sabate | first1 = JM. | last2 = Clotet | first2 = M. | last3 = Torrubia | first3 = S. | last4 = Gomez | first4 = A. | last5 = Guerrero | first5 = R. | last6 = de las Heras | first6 = P. | last7 = Lerma | first7 = E. | title = Radiologic evaluation of breast disorders related to pregnancy and lactation. | journal = Radiographics | volume = 27 Suppl 1 | issue = | pages = S101-24 | month = Oct | year = 2007 | doi = 10.1148/rg.27si075505 | PMID = 18180221 }}</ref> | ||
====Variants==== | ====Variants==== |
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