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Difference between revisions of "Heart valves"
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→Localized dystrophic heart valve amyloidosis
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==Localized dystrophic heart valve amyloidosis== | ==Localized dystrophic heart valve amyloidosis== | ||
===General=== | ===General=== | ||
*Common:<ref name=pmid6190729>{{Cite journal | last1 = Cooper | first1 = JH. | title = Localized dystrophic amyloidosis of heart valves. | journal = Hum Pathol | volume = 14 | issue = 7 | pages = 649-53 | month = Jul | year = 1983 | doi = | PMID = 6190729 }}</ref> | *Common: | ||
**~80<ref name=pmid6190729>{{Cite journal | last1 = Cooper | first1 = JH. | title = Localized dystrophic amyloidosis of heart valves. | journal = Hum Pathol | volume = 14 | issue = 7 | pages = 649-53 | month = Jul | year = 1983 | doi = | PMID = 6190729 }}</ref>-100%<ref name=pmid7223424>{{Cite journal | last1 = Falk | first1 = E. | last2 = Ladefoged | first2 = C. | last3 = Christensen | first3 = HE. | title = Amyloid deposits in calcified aortic valves. | journal = Acta Pathol Microbiol Scand A | volume = 89 | issue = 1 | pages = 23-6 | month = Jan | year = 1981 | doi = | PMID = 7223424 }} | |||
**~50% of valves with post-rheumatic sclerosis. | </ref> of valves with calcific degeneration, i.e. [[calcific aortic stenosis]]. | ||
**~50% of valves with post-rheumatic sclerosis.<ref name=pmid6190729/> | |||
*Not seen in acute disease and healed endocarditis.<ref name=pmid6190729/> | *Not seen in acute disease and healed endocarditis.<ref name=pmid6190729/> | ||
Hypothesis: | |||
*Amyloid deposition in the aortic valve is the precursor lesion of [[aortic calcific stenosis]].<ref name=pmid7223424/> | |||
===Microscopic=== | ===Microscopic=== | ||