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(→Fat necrosis: more) |
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==Fat | ==Fat necrosis of the breast== | ||
===General=== | |||
Etiology:<ref name=pmid19234281/> | |||
*Trauma, surgery. | |||
*Radiation. | |||
===Microscopic=== | ===Microscopic=== | ||
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*Dying/dead adipocytes: | *Dying/dead adipocytes: | ||
**Light pink "low density" whispy poorly demarcated blobs - lack a nucleus. | **Light pink "low density" whispy poorly demarcated blobs - lack a nucleus. | ||
** | **#Early: cellular outlines seen, light pink/loose cytoplasm. | ||
** | **#Mid: cellular outlines indistinct, dense pink cytoplasm. | ||
** | **#*Foamy macrophages - adjacent to fat. | ||
** | **#**Abundant cytoplasm with granular (pink) crap inside. | ||
** | **#**Oval nucleus with small nucleolus. | ||
** | **#Late: | ||
** | **#*Macrophages: multinucleated giant-cells. | ||
** | **#*Calcification. | ||
Notes: | Notes: |
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