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Difference between revisions of "Breast cytopathology"
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→Fat necrosis: more
(→Fat necrosis: more) |
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==Fat [[necrosis]]== | ==Fat [[necrosis]]== | ||
Features: | |||
*Dying adipocytes | ===Microscopic=== | ||
** | Features:<ref name=pmid19234281>{{Cite journal | last1 = Taboada | first1 = JL. | last2 = Stephens | first2 = TW. | last3 = Krishnamurthy | first3 = S. | last4 = Brandt | first4 = KR. | last5 = Whitman | first5 = GJ. | title = The many faces of fat necrosis in the breast. | journal = AJR Am J Roentgenol | volume = 192 | issue = 3 | pages = 815-25 | month = Mar | year = 2009 | doi = 10.2214/AJR.08.1250 | PMID = 19234281 | URL = http://www.ajronline.org/content/192/3/815.full }}</ref> | ||
*Foamy macrophages - adjacent to fat. | *Dying/dead adipocytes: | ||
**Abundant cytoplasm - with granular crap inside. | **Light pink "low density" whispy poorly demarcated blobs - lack a nucleus. | ||
**Oval nucleus with small nucleolus. | ***Early: cellular outlines seen, light pink - loose. | ||
***Mid: adipocytes collapsed/more dense. | |||
****Foamy macrophages - adjacent to fat. | |||
*****Abundant cytoplasm - with granular (pink) crap inside. | |||
*****Oval nucleus with small nucleolus. | |||
***Late: | |||
****Macrophages: multinucleated giant-cells. | |||
****Calcification. | |||
Notes: | |||
*Healthy adipocytes - large cells, clear cytoplasm. | |||
Images: | |||
*[http://www.ajronline.org/content/192/3/815/F1.expansion.html Early fat necrosis (ajronline.org)]. | |||
*[http://www.ajronline.org/content/192/3/815/F4.expansion.html Mid fat necrosis (ajronline.org)]. | |||
*[http://www.ajronline.org/content/192/3/815/F5.expansion.html Late fat necrosis (ajronline.org)]. | |||
*[http://www.ajronline.org/content/192/3/815/F6.expansion.html Late fat necrosis - calcifications (ajronline.org)]. | |||
==Adenocarcinoma== | ==Adenocarcinoma== | ||