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Difference between revisions of "Lymph node pathology"
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→Cat-scratch disease
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===General=== | ===General=== | ||
*[[AKA]] ''Cat-scratch fever''. | *[[AKA]] ''Cat-scratch fever''. | ||
*Infection caused | *Infection caused ''Bartonella henselae'',<ref name=pmid19332922>{{Cite journal | last1 = Jerris | first1 = RC. | last2 = Regnery | first2 = RL. | title = Will the real agent of cat-scratch disease please stand up? | journal = Annu Rev Microbiol | volume = 50 | issue = | pages = 707-25 | month = | year = 1996 | doi = 10.1146/annurev.micro.50.1.707 | PMID = 8905096 }}</ref> a gram-negative bacilla (0.3-1.0 x 0.6-3.0 micrometers) in chains, clumps, or singular.<ref name=Ref_ILNP110>{{Ref ILNP|110}}</ref> | ||
*Treatment: antibiotics. | *Treatment: antibiotics. | ||
===Clinical=== | |||
Features:<ref name=Ref_ILNP113>{{Ref ILNP|113}}</ref> | |||
*Usually unilateral. | |||
**May be desseminated in individuals with immune dysfunction. | |||
*Contact with cats. | |||
===Micrograph=== | ===Micrograph=== | ||
Features: | Features:<ref name=Ref_ILNP113>{{Ref ILNP|113}}</ref> | ||
* | *Necrotizing granulomas with: | ||
**Neutrophils present in microabscess (necrotic debris) - '''key feature'''. | |||
*+/-Multinucleated giant cells. | |||
Notes: | |||
*May involve capsule or perinodal tissue. | |||
Stains: | Stains: | ||
*Warthin-Starry stain. | *Warthin-Starry stain +ve. | ||
*B. henselae IHC stain +ve. | |||
Image(s): | Image(s): | ||