Difference between revisions of "Lymph node pathology"

Lymph node pathology (view source)

678 bytes added , 14:35, 3 August 2010

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 ===Microscopic===
-Features:<ref name=Ref_ILNP174>{{Ref_ILNP|174}}</ref>
+Features:<ref name=Ref_ILNP179>{{Ref_ILNP|179}}</ref>
-*Follicles of variable size, large follicles - '''key feature'''.
+*Enlarged follicles, follicle size variation - '''key feature''' with:
-**Centroblast 3-4x resting lymphocytes.
+**Large germinal centers (pale on H&E).
+***Mitoses common.
+***Variable lymphocyte morphology.
+***Tingible-body macrophage (large, pale cells with junk in the cytoplasm).
+**Rim of small (inactive) lymphocytes.
+IHC:
+*BCL-2 -ve.
 Image: [http://pleiad.umdnj.edu/hemepath/normal_node/normal_node.html Normal lymph node (umdnj.edu)].
+==Diffuse paracorticl hyperplasia==
+===General===
+*Benign.
+===Microscopic===
+Features:<ref name=Ref_ILNP179>{{Ref_ILNP|179}}</ref>
+*Interfollicular areas enlarged - '''key feature'''.
+**T cell population increased.
+**Plasma cells.
+**Macrophages.
+**Large Reed-Sternberg-like cells.
+==Sinus histiocytosis==
+===General===
+*Benign.
+===Microscopic===
+Features:<ref name=Ref_ILNP179>{{Ref_ILNP|179}}</ref>
+*Sinuses distended with histiocytes - '''key feature'''.
+*Plasma cells increased.
 ==Kikuchi disease==