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Difference between revisions of "Langerhans cell histiocytosis"
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Langerhans cell histiocytosis (view source)
Revision as of 01:33, 13 January 2012
, 01:33, 13 January 2012→Microscopic: w
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*Langerhans cells histiocytes - '''key feature'''. | *Langerhans cells histiocytes - '''key feature'''. | ||
**Clusters of cells (histiocytes) with a reniform (kidney-shaped) nucleus and abundant foamy cytoplasm. | **Clusters of cells (histiocytes) with a reniform (kidney-shaped) nucleus and abundant foamy cytoplasm. | ||
***Nucleus may look like a "coffee bean", i.e. have nuclear grooves (similar to those in [[papillary thyroid carcinoma]]) -- appearance dependent on the rotation of the nucleus.<ref>BN. 15 March 2011.</ref> | ***Nucleus may look like a "[[coffee bean nucleus|coffee bean]]", i.e. have nuclear grooves (similar to those in [[papillary thyroid carcinoma]]) -- appearance dependent on the rotation of the nucleus.<ref>BN. 15 March 2011.</ref> | ||
***Chromatin pattern: fine granular, light gray. | ***Chromatin pattern: fine granular, light gray. | ||
*+/-Eosinophils - often prominent. | *+/-Eosinophils - often prominent. | ||