Difference between revisions of "Breast pathology"

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==Apocrine metaplasia==
==Apocrine metaplasia==
===General===
*Benign/not significant.  Can be considered to be pretty wallpaper in the house of breast pathology.
===Etiology===
*Increased number of mitochondria.
**In other body sites this has different names, e.g. ''[[Hurthle cell change]]'' (thyroid), ''[[oncocytoma|oncocytic]] change'' (kidney - [[oncocytoma]], thyroid).
===Histology===
===Histology===
Features:
*Eosinophilic cytoplasm.
*Eosinophilic cytoplasm.


Note:  
Note:  
*Apocrine changes, i.e. cytoplasmic eosinophilia, can appear in malignant tumours; eosinophilia doesn't make it benign.
*Apocrine changes, i.e. cytoplasmic eosinophilia, can appear in malignant tumours; eosinophilia doesn't make it benign.
===Etiology===
*Increased number of mitochondria.
**In other body sites this has different names, e.g. ''[[Hurthle cell change]]'' (thyroid), ''[[oncocytoma|oncocytic]] change'' (kidney - [[oncocytoma]], thyroid).


===Significance===
==Fibrocystic change==
*Not significant. Can be considered to be pretty wallpaper in the house of breast pathology.
===General===
*Really common.
*Benign.
 
===Microscopic===
Features:
*Dilated glands - '''key change'''.
**Glands normal: two cell layers present.
*Often seen together with ''apocrine metaplasia''.


==Columnar cell change==
==Columnar cell change==
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