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==Apocrine metaplasia== | ==Apocrine metaplasia== | ||
===General=== | |||
*Benign/not significant. Can be considered to be pretty wallpaper in the house of breast pathology. | |||
===Etiology=== | |||
*Increased number of mitochondria. | |||
**In other body sites this has different names, e.g. ''[[Hurthle cell change]]'' (thyroid), ''[[oncocytoma|oncocytic]] change'' (kidney - [[oncocytoma]], thyroid). | |||
===Histology=== | ===Histology=== | ||
Features: | |||
*Eosinophilic cytoplasm. | *Eosinophilic cytoplasm. | ||
Note: | Note: | ||
*Apocrine changes, i.e. cytoplasmic eosinophilia, can appear in malignant tumours; eosinophilia doesn't make it benign. | *Apocrine changes, i.e. cytoplasmic eosinophilia, can appear in malignant tumours; eosinophilia doesn't make it benign. | ||
=== | ==Fibrocystic change== | ||
* | ===General=== | ||
*Really common. | |||
*Benign. | |||
===Microscopic=== | |||
Features: | |||
*Dilated glands - '''key change'''. | |||
**Glands normal: two cell layers present. | |||
*Often seen together with ''apocrine metaplasia''. | |||
==Columnar cell change== | ==Columnar cell change== |
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