48,830
edits
(→General: more still) |
m (→Microscopic) |
||
Line 165: | Line 165: | ||
Features:<ref name=pmid20871223>{{Cite journal | last1 = Torbenson | first1 = M. | last2 = Hart | first2 = J. | last3 = Westerhoff | first3 = M. | last4 = Azzam | first4 = RK. | last5 = Elgendi | first5 = A. | last6 = Mziray-Andrew | first6 = HC. | last7 = Kim | first7 = GE. | last8 = Scheimann | first8 = A. | title = Neonatal giant cell hepatitis: histological and etiological findings. | journal = Am J Surg Pathol | volume = 34 | issue = 10 | pages = 1498-503 | month = Oct | year = 2010 | doi = 10.1097/PAS.0b013e3181f069ab | PMID = 20871223 }}</ref> | Features:<ref name=pmid20871223>{{Cite journal | last1 = Torbenson | first1 = M. | last2 = Hart | first2 = J. | last3 = Westerhoff | first3 = M. | last4 = Azzam | first4 = RK. | last5 = Elgendi | first5 = A. | last6 = Mziray-Andrew | first6 = HC. | last7 = Kim | first7 = GE. | last8 = Scheimann | first8 = A. | title = Neonatal giant cell hepatitis: histological and etiological findings. | journal = Am J Surg Pathol | volume = 34 | issue = 10 | pages = 1498-503 | month = Oct | year = 2010 | doi = 10.1097/PAS.0b013e3181f069ab | PMID = 20871223 }}</ref> | ||
*Giant hepatocytes with multiple nuclei - '''key feature'''. | *Giant hepatocytes with multiple nuclei - '''key feature'''. | ||
**Typically 35% of hepatocytes affected. | **Typically ~35% of hepatocytes affected. | ||
*Minimal or absent inflammation portal and lobular inflammation. | *Minimal or absent inflammation portal and lobular inflammation. | ||
*Lobular cholestasis. | *Lobular cholestasis. |
edits