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Features: | Features: | ||
*Subcortical infarcts. | *Subcortical infarcts. | ||
**Patches of (non-myelinated) tissue within the white matter deep to the cortex with abundant macrophages. | |||
Note: | Note: | ||
*No cortical involvement. | *No cortical involvement -- this is unlike ''multiple sclerosis''. | ||
DDx: | DDx: | ||
*Amyloidosis. | *Amyloidosis. | ||
*Binswanger's disease - multi-infarct dementia affecting subcortical white | *Binswanger's disease - multi-infarct dementia affecting subcortical white matter. | ||
**Often diagnosed as ''Alzheimer's disease'' in the past. | **Often diagnosed as ''Alzheimer's disease'' in the past. | ||
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