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Difference between revisions of "Gastrointestinal tract polyps"
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→Microscopic: format
m (→Microscopic: inflammation) |
(→Microscopic: format) |
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| Line 145: | Line 145: | ||
===Traditional adenoma=== | ===Traditional adenoma=== | ||
====Microscopic==== | ====Microscopic==== | ||
*Nuclear changes | *Nuclear changes - '''key feature'''. | ||
**Loss of nuclear polarity (nuclei no longer on basement membrane) | **Loss of nuclear polarity (nuclei no longer on basement membrane). | ||
**Nuclear crowding/pseudostratification (key feature) | **Nuclear crowding/pseudostratification (key feature). | ||
**hyperchromasia | **hyperchromasia. | ||
**Cigar-shaped (elongated) nucleus - length:width > 3:1 (key feature) | **Cigar-shaped (elongated) nucleus - length:width > 3:1 (key feature). | ||
***Normal nuclei are round | ***Normal nuclei are round. | ||
*Loss/decrease of goblet cells | *Loss/decrease of goblet cells. | ||
*Cytoplasmic hyperchromasia | *Cytoplasmic hyperchromasia. | ||
====Typing==== | ====Typing==== | ||