Simian virus 40

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Simian virus 40
Immunostain in short

SV40 immunostain in polyomavirus nephropathy.
Normal staining pattern nuclear
Positive polyomavirus nephropathy, progressive multifocal leukoencephalopathy

Simian virus 40, commonly known as SV40, is an immunostain for polyomavirus. It is a nuclear stain.

It is used in the diagnosis of:

See also


  1. Lautenschlager, I.; Jahnukainen, T.; Kardas, P.; Lohi, J.; Auvinen, E.; Mannonen, L.; Dumoulin, A.; Hirsch, HH. et al. (Dec 2014). "A case of primary JC polyomavirus infection-associated nephropathy.". Am J Transplant 14 (12): 2887-92. doi:10.1111/ajt.12945. PMID 25359127.
  2. Muñoz-Mármol, AM.; Mola, G.; Fernández-Vasalo, A.; Vela, E.; Mate, JL.; Ariza, A. (Nov 2004). "JC virus early protein detection by immunohistochemistry in progressive multifocal leukoencephalopathy: a comparative study with in situ hybridization and polymerase chain reaction.". J Neuropathol Exp Neurol 63 (11): 1124-30. PMID 15581180.