Sclerotic metastasis

Sclerotic metastasis refers the imaging appearance of metastatic disease. Sclerotic metastases are less common than lytic metastases.

The classic sclerotic metastases are:

• Breast cancer.
• Prostate cancer.

Sclerotic bone lesions which are not strictly metastases can also be seen in:

• Systemic mastocytosis
• Certain forms of myeloma (e.g. so-called "osteosclerotic" myeloma in POEMS syndrome)

See also

• Lytic metastasis.