From Libre Pathology
Jump to navigation Jump to search
Micrograph showing Sarcina. H&E stain. (WC/Librepath)

Sarcina organisms are occasionally seen in the gastrointestinal tract. They are reported in urine.[1]


  • Probably a commensal organism.[2]
  • Gram positive coccus.[1]
  • Uncommonly seen.
  • Associated with gastroparesis,[2] as may be seen in diabetes mellitus.

Described complications:[2]

  • Gastric perforation.
  • Emphysematous gastritis.


  • Sarcina ventriculi = Gram-positive organism.[2]



  • Erythema.
  • +/-Gastric ulcer.
  • +/-Retained food.



  • Small essentially spherical micro-organisms.
    • Each micro-organism 1.8-3 micrometres - purple on H&E stain.
    • Arranged in clusters of 4, 8 or more - classically in a tetrad - key feature.


  • Micrococcus - form larger clusters.[3]


Case 1


Sign out

Urine cytology

Abundant micro-organisms compatible with Sarcina, see comment.
Acute inflammation.
NEGATIVE for High-Grade Urothelial Carcinoma.

The micro-organisms are arranged in distinctive tetrads, as is typical for Sarcina.
This is an uncommon finding.[1] Treatment should be considered within the clinical context.

1. Bommannan K, Gaspar BL, Sachdeva MUS. BMJ Case Rep. 2016 Oct 13;2016:bcr2016216991. doi:10.1136/bcr-2016-216991

See also


  1. 1.0 1.1 Bommannan K, Gaspar BL, Sachdeva MU (October 2016). "Pathogenic Sarcina in urine". BMJ Case Rep 2016. doi:10.1136/bcr-2016-216991. PMC 5073697. PMID 27737866.
  2. 2.0 2.1 2.2 2.3 2.4 Ratuapli, SK.; Lam-Himlin, DM.; Heigh, RI. (2013). "Sarcina ventriculi of the stomach: a case report.". World J Gastroenterol 19 (14): 2282-5. doi:10.3748/wjg.v19.i14.2282. PMID 23599657.
  3. 3.0 3.1 Lam-Himlin, D.; Tsiatis, AC.; Montgomery, E.; Pai, RK.; Brown, JA.; Razavi, M.; Lamps, L.; Eshleman, JR. et al. (Nov 2011). "Sarcina organisms in the gastrointestinal tract: a clinicopathologic and molecular study.". Am J Surg Pathol 35 (11): 1700-5. doi:10.1097/PAS.0b013e31822911e6. PMID 21997690.