Squamous metaplasia of lactiferous ducts

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Squamous metaplasia of lactiferous ducts, abbreviated SMOLD, is an uncommon benign change is in the breast typically seen in post-menuopausal women.

General

  • Uncommon.[1]
  • Associated with smoking.[1]
  • Post-menopausal women.
  • May be associated with subareolar abscess.

Gross

  • +/-Nipple inversion.[2]

Microscopic

Features:

  • Squamous epithelium - replaces (bilayered) lactiferous ducts - key feature.[2]
  • Xanthomatous reaction.

Images

  • SMOLD - very low mag. (WC/Nephron)

  • SMOLD - low mag. (WC/Nephron)

See also

References

  1. ↑ 1.0 1.1 Lo, G.; Dessauvagie, B.; Sterrett, G.; Bourke, AG. (Nov 2012). "Squamous metaplasia of lactiferous ducts (SMOLD).". Clin Radiol 67 (11): e42-6. doi:10.1016/j.crad.2012.07.011. PMID 22964367.
  2. ↑ 2.0 2.1 Powell, BC.; Maull, KI.; Sachatello, CR. (Aug 1977). "Recurrent subareolar abscess of the breast and squamous metaplasia of the lactiferous ducts: a clinical syndrome.". South Med J 70 (8): 935-7. PMID 887978.
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