From Libre Pathology
|Diagnosis in short|
Pulmonary infarct. H&E stain.
|LM||necrosis of alveolar walls - loss of nuclei, alveolar hemorrhage, +/-evidence of underlying cause|
|LM DDx||see Associated Dx|
|Gross||lung periphery, classically described as wedge-shaped|
|Associated Dx||underlying causes: sickle cell disease, pulmonary embolism, vasculitides, malignancy (e.g. lymphoma), drug toxicity, others|
|Radiology||reverse halo sign|
|Prognosis||dependent on underlying cause|
|Treatment||dependent on underlying cause|
Pulmonary infarct is the death of lung tissue due to oxygen deprivation.
It is also known as a lung infarct, lung infarction, and pulmonary infarction.
- Uncommon because of the dual blood supply (systemic via the bronchial arteries, pulmonary via the pulmonary arteries).
Less common causes:
- Lung periphery, classically described as wedge-shaped.
- In a histologic section, the classic wedge-shaped infarct is triangular:
- Base of triangle on the pleural aspect.
- Point furthest from the pleura close to the compromised artery that lead to infarction.
- Reverse halo sign.
- Necrosis of alveolar walls - loss of nuclei.
- Alveolar hemorrhage.
- URL: http://emedicine.medscape.com/article/908045-overview. Accessed on: 12 April 2012.
- Casullo, J.; Semionov, A. (Feb 2013). "Reversed halo sign in acute pulmonary embolism and infarction.". Acta Radiol. doi:10.1177/0284185113475797. PMID 23395814.