Pilar sheath acanthoma
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| Pilar sheath acanthoma | |
|---|---|
| Diagnosis in short | |
 Possibly a pilar sheath acanthoma. H&E stain. | |
|
| |
| LM | cystic cavity with branching - contains keratineous material, usually extends from surface to deep cutis, cyst lining consists of a thickened squamous epithelium |
| LM DDx | trichofolliculoma, dilated pore of Winer, epidermal inclusion cyst |
| Gross | raised lesion, central cavitation |
| Site | skin - classically upper lip |
|
| |
| Clinical history | typically middle aged - 50s |
| Prevalence | rare |
| Prognosis | benign |
Pilar sheath acanthoma is a rare benign skin lesion.
General
- Rare.[1]
- Considered a hamartoma.[1]
- Does not regress like keratoacanthoma.
- Typically middle aged individuals - median age in one series 55 years old, range 46-75 years old.[2]
Gross
- Raised lesion with a central depression - somewhat similar to keratoacanthoma.
- Classcially upper lip.[2]
DDx:
Microscopic
Features:[2]
- Cystic cavity with branching:[3]
- Contains keratineous material.
- Usually extends from surface to deep cutis - like a hair shaft.
- Cyst lining consists of a thickened squamous epithelium (acanthosis).
- +/-Mitoses.
DDx:
- Trichofolliculoma - no branching of cavity, associated with hair & sebaceous glands.[3]
- Dilated pore of Winer - associated with hair & sebaceous glands.[3]
- Epidermal inclusion cyst - no branching, no accessory structures.
Images
Possibly a pilar sheath acanthoma. (WC)
www:
- Pilar sheath acanthoma (nih.gov).[4]
- Pilar sheath acanthoma - several images (dermnet.org.nz).
- Pilar sheath acanthoma (eymj.org).[3]
- Pilar sheath acanthoma - several images (dermatopathonline.com).
See also
References
- ↑ 1.0 1.1 Vakilzadeh, F. (Jan 1987). "[Pilar sheath acanthoma].". Hautarzt 38 (1): 40-2. PMID 3557980.
- ↑ 2.0 2.1 2.2 Mehregan, AH.; Brownstein, MH. (Oct 1978). "Pilar sheath acanthoma.". Arch Dermatol 114 (10): 1495-7. PMID 718186.
- ↑ 3.0 3.1 3.2 3.3 Choi, YS.; Park, SH.; Bang, D. (Dec 1989). "Pilar sheath acanthoma--report of a case with review of the literature.". Yonsei Med J 30 (4): 392-5. PMID 2697113.
- ↑ Bavikar, RR.; Gaopande, V.; Deshmukh, SD. (Jan 2011). "Postauricular pilar sheath acanthoma.". Int J Trichology 3 (1): 39-40. doi:10.4103/0974-7753.82136. PMID 21769237.