Pericardial cyst

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Pericardial cyst is a rare benign pathology of the pericardium.

General

  • Rare - 1 in 100,000.[1][2]
  • Approximately 8% of mediastinal masses.[2]
  • Generally believed to be congenital; however, documented development on imaging reported.[3]

Gross

  • Typical location: right cardiophrenic angle.[1]

Microscopic

Features:

  • Mesothelial cyst - simple epithelium without cilia.

DDx:

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Mediastinal Lesion, Surgical Excision:
- Benign cyst with a fibrotic wall lined by a simple epithelium, compatible 
  with clinical impression of pericardial cyst.
- NEGATIVE for malignancy.

See also

References

  1. 1.0 1.1 Peebles CR, Shambrook JS, Harden SP (December 2011). "Pericardial disease--anatomy and function". Br J Radiol 84 Spec No 3: S324–37. doi:10.1259/bjr/16168253. PMC 3473919. PMID 22723538. //www.ncbi.nlm.nih.gov/pmc/articles/PMC3473919/.
  2. 2.0 2.1 Seo, GW.; Seol, SH.; Jeong, HJ.; Seo, MG.; Song, PS.; Kim, DK.; Kim, KH.; Kim, DI. et al. (Dec 2014). "A large pericardial cyst compressing the left atrium presenting as a pericardiopleural efussion.". Heart Lung Circ 23 (12): e273-5. doi:10.1016/j.hlc.2014.08.011. PMID 25240572.
  3. Comoglio, C.; Sansone, F.; Delsedime, L.; Campanella, A.; Ceresa, F.; Rinaldi, M. (2010). "Mesothelial cyst of the pericardium, absent on earlier computed tomography.". Tex Heart Inst J 37 (3): 354-7. PMID 20548822.