Microglandular adenosis
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Microglandular adenosis, abbreviated MGA, is a benign pathology of the breast.
Not to be confused with microglandular hyperplasia.
General
- Controversial thingy.
Management:
- Excision.
Microscopic
Features:[1]
- Round glands lined by a single layer of cells.
- May extend into fat.
- Lack of desmoplastic stroma.
DDx:
- Tubular carcinoma - has apical snouts, desmoplasia among other things; see page by Collins.[1]
- Sclerosing adenosis.
Images
- Microglandular adenosis (surgical pathologyatlas.com).
- MGA - low mag. (webpathology.com).
- MGA - high mag. (webpathology.com).
- MGA (breastpathology.info).
- MGA - several images (breastpathology.info).
IHC
Features:[2]
- S100 +ve.
- 34BE12 +ve -- focal!
Others:
See also
References
- ↑ 1.0 1.1 URL: http://www.uscap.org/site~/iap2006/slides08-4v.htm. Accessed on: 18 May 2011.
- ↑ Joshi, MG.; Lee, AK.; Pedersen, CA.; Schnitt, S.; Camus, MG.; Hughes, KS. (Jan 1996). "The role of immunocytochemical markers in the differential diagnosis of proliferative and neoplastic lesions of the breast.". Mod Pathol 9 (1): 57-62. PMID 8821958.
- ↑ Lefkowitch, Jay H. (2006). Anatomic Pathology Board Review (1st ed.). Saunders. pp. 296 Q20. ISBN 978-1416025887.