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The epididymis is a mostly forgotten organ associated with the testis. It is rarely afflicited by tumours.[1]

Normal histology


  • Tubular structures lined by a pseudostratified epithelium with cilia.


  • Epididymis may have clear luminal cells focally.



The epididymis' luminal cells stain with:

  • CK7 (diffuse).
  • p63 (patchy).


  • Clear cells are may be seen; they are NEGATIVE for D2-40, PLAP and CD117.


See also


  1. Yeung, CH.; Wang, K.; Cooper, TG. (May 2012). "Why are epididymal tumours so rare?". Asian J Androl 14 (3): 465-75. doi:10.1038/aja.2012.20. PMID 22522502.
  2. Toutziaris, C.; Kampantais, S.; Perdikis, I.; Gourvas, V.; Laskaridis, L.; Gkagkalidis, K.; Lakis, S.; Ioannidis, S. (2013). "Papillary cystadenoma of epididymis: Is there a need for further investigation in unilateral cases?". Int J Surg Case Rep 4 (7): 616-8. doi:10.1016/j.ijscr.2013.03.038. PMID 23708309.
  3. Odrzywolski, KJ.; Mukhopadhyay, S. (Apr 2010). "Papillary cystadenoma of the epididymis.". Arch Pathol Lab Med 134 (4): 630-3. doi:10.1043/1543-2165-134.4.630. PMID 20367315.
  4. Parker, SG.; Kommu, SS. (2013). "Post-intravesical BCG epididymo-orchitis: Case report and a review of the literature.". Int J Surg Case Rep 4 (9): 768-70. doi:10.1016/j.ijscr.2013.05.017. PMID 23856256.
  5. Bulbul, MA.; Hijaz, A.; Beaini, M.; Araj, GF.; Tawil, A.. "Tuberculous epididymo-orchitis following intravesical BCG for superficial bladder cancer.". J Med Liban 50 (1-2): 67-9. PMID 12841318.
  6. Klimis, T.; Vlahos, P.; Kokotas, N.. "Serous cystadenoma of the epididymis of common epithelial ovarian type: case report with an immunohistochemical study.". J BUON 11 (2): 237-40. PMID 17318978.