Identity testing
(Redirected from DNA identity testing)
Jump to navigation
Jump to search
Identity testing, formally DNA identity testing, is often seen on TV shows. It is used in forensic pathology and surgical pathology.
Technique
- Looks for short tandem repeats in non-coding regions of the genome.
Uses
- Tissue floater.[1]
- Suspected specimen mix-ups.[2]
- Decendent identification - uncommonly used, despite the impression one may have from TV shows.
- Chimerism analysis - post-bone marrow transplantation.[3]
See also
Reference
- ↑ Mosse, CA.; Stumph, JR.; Best, DH.; Vnencak-Jones, CL. (Sep 2009). "A B-cell lymphoma diagnosed in floater tissue: implications of the diagnosis and resolution of a laboratory error.". Am J Med Sci 338 (3): 248-51. doi:10.1097/MAJ.0b013e3181a88dc0. PMID 19745614.
- ↑ Cao, D.; Hafez, M.; Berg, K.; Murphy, K.; Epstein, JI. (Apr 2005). "Little or no residual prostate cancer at radical prostatectomy: vanishing cancer or switched specimen?: a microsatellite analysis of specimen identity.". Am J Surg Pathol 29 (4): 467-73. PMID 15767799.
- ↑ Borrill, V.; Schlaphoff, T.; du Toit, E.; Marx, M.; Wood, L.; Jacobs, P. (Aug 2008). "The use of short tandem repeat polymorphisms for monitoring chimerism following bone marrow transplantation: a short report.". Hematology 13 (4): 210-4. doi:10.1179/102453308X316059. PMID 18796246.