Cronkhite-Canada syndrome

From Libre Pathology
Jump to navigation Jump to search

Cronkhite-Canada syndrome, abbreviated CCS, is a very rare syndrome with hamartomatous polyps and ectodermal abnormalities.

General

Clinical features:[1]

Microscopic

Features:

  • Polyps have same morphology as juvenile polyps/retension polyps.
  • Crypt dilation and edema in non-polypoid mucosa[2] - key feature.

DDx:

Images

See also

References

  1. Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso Fausto; Robbins, Stanley L.; Abbas, Abul K. (2005). Robbins and Cotran pathologic basis of disease (7th ed.). St. Louis, Mo: Elsevier Saunders. pp. 858-9. ISBN 0-7216-0187-1.
  2. Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 430. ISBN 978-1416054542.