Cerebrovascular accident

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Cerebrovascular accident, abbreviated CVA, is a common neurologic pathology. It is also known as a stroke.

General

  • Very common.
  • Leading cause of morbidity and mortality.

Etiologies:[1]

Clinical classification:

  1. Hemorrhagic stroke.
  2. Ischemic stroke.

Gross

  • Soft/mushy brain.
  • Older infarcts.
    • A "roof" is present - a thin submeningeal layer is preserved by the CSF.[2]
      • "Roof" is absent in trauma.
    • Cavity - in older infarcts.
  • Laminar necrosis = (thin) chalky line replaces grey mater.[3]
    • AKA pseudolaminar necrosis - as it is not localized to a specific layer of the cortex.[4]

DDx:

Images

Microscopic

Features:

DDx:

  • Hypoglycaemic injury.[1]

Images

See also

References

  1. 1.0 1.1 Love, S. (Feb 2011). "Autopsy approach to stroke.". Histopathology 58 (3): 333-51. doi:10.1111/j.1365-2559.2010.03614.x. PMID 20666847.
  2. MUN. 16 December 2009.
  3. URL: http://moon.ouhsc.edu/kfung/jty1/neurotest/Q03-Ans.htm. Accessed on: 26 October 2010.
  4. MUN. 26 November 2010.