Anastomosing hemangioma of the kidney

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Anastomosing hemangioma of the kidney
Diagnosis in short

Anastomosing hemangioma of the kidney. H&E stain.

Synonyms renal anastomosing hemangioma

LM vascular tumour with architecture similar to splenic sinsoids, hobnailing, +/-hyaline globules, +/-extramedullary hematopoiesis
LM DDx angiosarcoma, other hemangiomas, other vascular tumours
IHC CD34 +ve, CD31 +ve, HHV-8
Gross brown/mahogany lesion, classically centered on medulla of kidney
Grossing notes total nephrectomy for tumour grossing, partial nephrectomy grossing
Site kidney

Associated Dx +/-end stage renal disease
Prevalence very rare
Prognosis benign

Anastomosing hemangioma of the kidney a rare benign vascular tumour of kidney that may mimic angiosarcoma.[1]

General

  • Rare - case reports.
    • The bigger category vascular tumours of the kidney is rare; in the world literature (as of 2015), according to Omiyale, there are approximately 40 angiosarcoma and 220 hemangiomas.[2]
  • Typically seen in end stage renal disease.[3]

Gross

Features:

  • Mahogany/brown - centered on medulla of kidney.[3]

Microscopic

Features:

Note:

  • Tumour may extend into surrounding adipose tissue.

DDx:

Images

IHC

Features:[3]

  • CD31 +ve.
  • CD34 +ve.
  • HHV8 -ve.

See also

References

  1. Montgomery, E.; Epstein, JI. (Sep 2009). "Anastomosing hemangioma of the genitourinary tract: a lesion mimicking angiosarcoma.". Am J Surg Pathol 33 (9): 1364-9. doi:10.1097/PAS.0b013e3181ad30a7. PMID 19606014.
  2. Omiyale, AO. (Jul 2015). "Anastomosing hemangioma of the kidney: a literature review of a rare morphological variant of hemangioma.". Ann Transl Med 3 (11): 151. doi:10.3978/j.issn.2305-5839.2015.06.16. PMID 26244138.
  3. 3.0 3.1 3.2 3.3 Kuroda, N.; Ohe, C.; Deepika, S.; Yorita, K.; Mikami, S.; Furuya, M.; Nagashima, Y.; Hes, O. et al. (Jun 2016). "Review of renal anastomosing hemangioma with focus on clinical and pathological aspects.". Pol J Pathol 67 (2): 97-101. PMID 27543862.