Adenovirus appendicitis

From Libre Pathology
Jump to: navigation, search

Adenovirus appendicitis is a rare inflammatory condition of the appendix.

General

  • Rare type of appendicitis in children.
  • Classically found in association with intussusception or mesenteric adenitis .
  • Caused by Adenovirus.

Microscopic

Features:[1]

  • Lymphoid hyperplasia - key feature.
  • +/-Adenovirus inclusions; "smudge cells".

Notes:

  • The classic finding of appendicitis (neutrophils infiltrating into the muscularis propria) may be absent.[1]

Image:

IHC

  • Adenovirus +ve = diagnostic.

See also

References

  1. 1.0 1.1 1.2 Grynspan, D.; Rabah, R.. "Adenoviral appendicitis presenting clinically as acute appendicitis.". Pediatr Dev Pathol 11 (2): 138-41. doi:10.2350/07-06-0299.1. PMID 17990936. Cite error: Invalid <ref> tag; name "pmid17990936" defined multiple times with different content