Difference between revisions of "Vimentin"
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| Line 9: | Line 9: | ||
Common tumours: | Common tumours: | ||
*[[Renal cell carcinoma]].<ref name=pmid18318577/> | *[[Renal cell carcinoma]].<ref name=pmid18318577/> | ||
*[[Endometrial carcinoma]].<ref name=pmid12647218/> | *[[Endometrial carcinoma]].<ref name=pmid12647218>{{Cite journal | last1 = Alkushi | first1 = A. | last2 = Irving | first2 = J. | last3 = Hsu | first3 = F. | last4 = Dupuis | first4 = B. | last5 = Liu | first5 = CL. | last6 = Rijn | first6 = M. | last7 = Gilks | first7 = CB. | title = Immunoprofile of cervical and endometrial adenocarcinomas using a tissue microarray. | journal = Virchows Arch | volume = 442 | issue = 3 | pages = 271-7 | month = Mar | year = 2003 | doi = 10.1007/s00428-002-0752-4 | PMID = 12647218 }}</ref> | ||
*[[Ovarian serous carcinoma]].<ref name=pmid18318577>{{Cite journal | last1 = Bahrami | first1 = A. | last2 = Truong | first2 = LD. | last3 = Ro | first3 = JY. | title = Undifferentiated tumor: true identity by immunohistochemistry. | journal = Arch Pathol Lab Med | volume = 132 | issue = 3 | pages = 326-48 | month = Mar | year = 2008 | doi = 10.1043/1543-2165(2008)132[326:UTTIBI]2.0.CO;2 | PMID = 18318577 }}</ref> | *[[Ovarian serous carcinoma]].<ref name=pmid18318577>{{Cite journal | last1 = Bahrami | first1 = A. | last2 = Truong | first2 = LD. | last3 = Ro | first3 = JY. | title = Undifferentiated tumor: true identity by immunohistochemistry. | journal = Arch Pathol Lab Med | volume = 132 | issue = 3 | pages = 326-48 | month = Mar | year = 2008 | doi = 10.1043/1543-2165(2008)132[326:UTTIBI]2.0.CO;2 | PMID = 18318577 }}</ref> | ||
*[[Papillary thyroid carcinoma]].<ref name=pmid18318577/> | *[[Papillary thyroid carcinoma]].<ref name=pmid18318577/> | ||
| Line 26: | Line 26: | ||
Common tumours that uncommonly have the pattern: | Common tumours that uncommonly have the pattern: | ||
*[[Gastric adenocarcinoma]].<ref>URL: [http://cat.inist.fr/?aModele=afficheN&cpsidt=2504165 http://cat.inist.fr/?aModele=afficheN&cpsidt=2504165]. Accessed on: 26 April 2011.</ref> | *[[Gastric adenocarcinoma]].<ref>URL: [http://cat.inist.fr/?aModele=afficheN&cpsidt=2504165 http://cat.inist.fr/?aModele=afficheN&cpsidt=2504165]. Accessed on: 26 April 2011.</ref> | ||
==Negative== | ==Negative== | ||
*Most [[carcinoma]]s. | *Most [[carcinoma]]s. | ||
Revision as of 23:20, 1 August 2016
Vimentin staining in a poorly differentiated carcinoma.
Vimentin is a common immunostain. It marks most soft tissue lesions and malignant melanoma. It is usually negative in carcinoma.
Positive
- Most sarcomas.
- Malignant melanoma.[1]
Vimentin and cytokeratin positivity
Common tumours:
- Renal cell carcinoma.[2]
- Endometrial carcinoma.[3]
- Ovarian serous carcinoma.[2]
- Papillary thyroid carcinoma.[2]
- Sarcomatoid carcinoma (spindle cell carcinoma).[2]
Rare tumours:
- Synovial sarcoma.[4]
- Rhabdoid tumour.[5]
- Epithelioid sarcoma.[6]
- Epithelioid angiosarcoma.[2]
- Desmoplastic small round cell tumour.[2]
- Anaplastic thyroid carcinoma.[2]
- Biphasic malignant mesothelioma.[2]
- Carcinosarcoma.[2]
Common tumours that uncommonly have the pattern:
Negative
- Most carcinomas.
See also
References
- ↑ Mısır, AF.; Durmuşlar, MC.; Zerener, T.; Gün, BD. (Apr 2016). "Primary malignant melanoma.". Saudi Med J 37 (4): 446-9. doi:10.15537/smj.2016.4.15017. PMID 27052289.
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 Bahrami, A.; Truong, LD.; Ro, JY. (Mar 2008). "Undifferentiated tumor: true identity by immunohistochemistry.". Arch Pathol Lab Med 132 (3): 326-48. doi:10.1043/1543-2165(2008)132[326:UTTIBI]2.0.CO;2. PMID 18318577.
- ↑ Alkushi, A.; Irving, J.; Hsu, F.; Dupuis, B.; Liu, CL.; Rijn, M.; Gilks, CB. (Mar 2003). "Immunoprofile of cervical and endometrial adenocarcinomas using a tissue microarray.". Virchows Arch 442 (3): 271-7. doi:10.1007/s00428-002-0752-4. PMID 12647218.
- ↑ Llombart-Bosch A, Lopez-Guerrero JA, Peydro-Olaya A (2002). "Synovial sarcoma (SS): new perspectives supported by modern technology". Arkh. Patol. 64 (3): 39–47. PMID 15338724.
- ↑ Itakura E, Tamiya S, Morita K, et al. (September 2001). "Subcellular distribution of cytokeratin and vimentin in malignant rhabdoid tumor: three-dimensional imaging with confocal laser scanning microscopy and double immunofluorescence". Mod. Pathol. 14 (9): 854–61. doi:10.1038/modpathol.3880401. PMID 11557780. http://www.nature.com/modpathol/journal/v14/n9/full/3880401a.html.
- ↑ Miettinen M, Fanburg-Smith JC, Virolainen M, Shmookler BM, Fetsch JF (August 1999). "Epithelioid sarcoma: an immunohistochemical analysis of 112 classical and variant cases and a discussion of the differential diagnosis". Hum. Pathol. 30 (8): 934–42. PMID 10452506.
- ↑ URL: http://cat.inist.fr/?aModele=afficheN&cpsidt=2504165. Accessed on: 26 April 2011.