Difference between revisions of "Synaptophysin"
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==Normal tissues== | ==Normal tissues== | ||
* | * Note: resists autolytic degradation (can be used 5 days post mortem). | ||
* Marker of late onset (neuronal maturation). | |||
===Positive staining=== | |||
* Cerebral cortex | |||
* Hippocampus | |||
* Corpus striatum, | |||
* Globus pallidus | |||
* Substantia nigra | |||
* Cerebellum system | |||
* Olfactory bulb | |||
== | ==Tumours== | ||
* | * [[Ganglioglioma]] | ||
* [[Medulloblastoma]] +/-ve. | |||
* [[Pituitary adenoma]] | |||
===Negative staining=== | |||
Revision as of 11:55, 8 April 2019
Synaptophysin staining in Atypical carcinoid.
Synaptophysin is the principal structural element of the walls of synaptic vesicles and thus a neuroendocrine marker.
Normal tissues
- Note: resists autolytic degradation (can be used 5 days post mortem).
- Marker of late onset (neuronal maturation).
Positive staining
- Cerebral cortex
- Hippocampus
- Corpus striatum,
- Globus pallidus
- Substantia nigra
- Cerebellum system
- Olfactory bulb
Tumours