Simian virus 40

From Libre Pathology
Jump to navigation Jump to search

Simian virus 40, commonly known as SV40, is an immunostain for polyomavirus. It is a nuclear stain.

Simian virus 40
Immunostain in short

SV40 immunostain in polyomavirus nephropathy.
Normal staining pattern nuclear
Positive polyomavirus nephropathy, progressive multifocal leukoencephalopathy

It is used in the diagnosis of:

See also


  1. Lautenschlager, I.; Jahnukainen, T.; Kardas, P.; Lohi, J.; Auvinen, E.; Mannonen, L.; Dumoulin, A.; Hirsch, HH. et al. (Dec 2014). "A case of primary JC polyomavirus infection-associated nephropathy.". Am J Transplant 14 (12): 2887-92. doi:10.1111/ajt.12945. PMID 25359127.
  2. Muñoz-Mármol, AM.; Mola, G.; Fernández-Vasalo, A.; Vela, E.; Mate, JL.; Ariza, A. (Nov 2004). "JC virus early protein detection by immunohistochemistry in progressive multifocal leukoencephalopathy: a comparative study with in situ hybridization and polymerase chain reaction.". J Neuropathol Exp Neurol 63 (11): 1124-30. PMID 15581180.